FDA Alert Regarding Flea and Tick Medication

By September 28, 2018Uncategorized
Partridge Animal Hospital

FDA Alert

On September 20, the U.S. Food and Drug Administration Center for Veterinary Medicine (FDA-CVM) released a public health advisory regarding an important safety message that will be added to the labels of all dog and cat drugs in the isoxazoline class. You can click here to read the message in its entirety.

Simparica flea medication for dogs
NexGard flea and tick medication for dogs
Bravecto flea medication for dogs
Bravecto flea medication for cats
Credelio flea medication for dogs

What You Should Know

  • The information that will be added to all isoxazoline labels identifies the potential for neurologic adverse reactions.
    • The labeling for Simparica® (sarolaner) Chewables has always included information about the potential for neurologic signs such as tremors, unsteadiness, and/or seizures that have been associated with use of it in some dogs.
    • Merial updated the NexGard®(afoxolaner) Chewables label to include the new precaution when they added the Lyme Disease prevention claim to the label.
    • The labeling for BRAVECTO® (fluralaner) – Topical Solution for Cats‎ and Dogs already includes the precaution about the potential for neurologic signs.
    • Merck will have to update the BRAVECTO® (fluralaner) Flavored Chews for Dogs prescribing information to include information about possible neurologic adverse reactions in the precautions section.
    • Elanco will have to update the Credelio®(lotilaner) Chewable Tablets prescribing information to include information about possible neurologic adverse reactions in the precautions section.
  • As is noted in the public advisory, the FDA-CVM carefully reviewed studies and other data on all isoxazolines prior to approval, and these products continue to be safe and effective for the majority of animals.
  • The most commonly reported adverse events globally are:
    • Vomiting
    • Diarrhea
    • Lethargy

FDA-CVM has also provided a fact sheet for pet owners. You can click here for a copy.

We have been prescribing these products since Nexgard was released five years ago and have not had any patients with neurologic symptoms. In fact, we have switched patients with seizures from Trifexis to NexGard because of the adverse reactions associated with Trifexis.

Here is a video with more information:

Vets: Don’t Misconstrue FDA Warning on Flea Meds

When Dr. Harvey Partridge built the St.Petersburg veterinary hospital in 1978, it was originally named “Riviera Animal Hospital”. In 1995, he sold the practice to a corporation of veterinary hospitals named VCA (Veterinary Centers of America). Dr. Partridge left the practice in 2003, and VCA’s lease ran out two years later. At that time, the St. Petersburg animal hospital was remodeled and opened under the new name, “Partridge Animal Hospital”.Dr. David Landers began working at Partridge Animal Hospital in St. Petersburg in 2007, and he purchased the practice from Dr. Partridge in 2010.

Dr. Freeborg did two externships with Dr. Partridge and Dr. Landers while he was in school. Dr. Landers was so impressed with him that he thought he would be a good fit for our clients and staff.

We see mostly dogs and cats with the occasional pocket pet and rabbit. The doctors enjoy working up challenging cases by utilizing the digital x-ray, ultrasound, brand new in-house lab machines, and endoscopy to come up with a diagnosis and then figure out the best way to treat it.

Dr. Landers first met the K9 unit supervisor when he was called out to our hospital for a false alarm response. Dr. Landers invited Officer Ladd into the hospital for a tour and expressed an interest in the dogs’ care. Officer Ladd was impressed by Dr. Landers enthusiasm and the hospital so he started sending the K9 unit dogs over for us to care for them. We see them for their wellness care, but also for emergency visits and everything in-between.

We are also the hospital for a local non-profit rescue, Pawlicious Poochie Pet Rescue. They rescue small, senior dogs that are on the kill list at the shelters and “fix” them up for adoption.

We are located at:

6400 4th St N.

St. Petersburg, FL 33702

Phone: (727) 526-8700

Fax: (727) 526-8755

Hours: Monday through Friday 8 a.m. – 6 p.m | Saturday 8 a.m. – 2 p.m.